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CHN2, Goat, Polyclonal Antibody, Abnova™

Product Code. 16091617
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Quantity:
100 μg
Unit Size:
100µg
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16091617 100 μg 100µg
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Product Code. 16091617 Supplier Abnova Supplier No. PAB15616.100ug

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Description

Goat polyclonal antibody raised aganist synthetic peptide of CHN2.

This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Sequence: C-QILIENEDVLF

Specifications

Antigen CHN2
Applications ELISA, Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised aganist synthetic peptide of CHN2.
Dilution ELISA (1:8000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene CHN2
Gene Accession No. NP_001035025.1
Gene Alias ARHGAP3/BCH/MGC138360/RHOGAP3
Gene Symbols CHN2
Host Species Goat
Immunogen A synthetic peptide corresponding to C-terminus of human CHN2.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1124
Test Specificity This antibody is expected to recognize both reported isoforms (NP_004058.1; NP_001035025.1).
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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