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CMA1, Goat, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of CMA1.
Brand: Abnova PAB27585.100ug
This item is not returnable.
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Description
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq
Sequence: QFRHPKYNTSTLHHDSpecifications
| CMA1 | |
| Polyclonal | |
| Unconjugated | |
| ELISA (1:32000) Western Blot (0.5-2ug/ml) The optimal working dilution should be determined by the end user. | |
| CMA1 | |
| CYH/MCT1/MGC119890/MGC119891/chymase | |
| Goat | |
| Affinity Purified | |
| RUO | |
| 1215 | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Western Blot | |
| 0.5 mg/mL | |
| Goat polyclonal antibody raised against synthetic peptide of CMA1. | |
| In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA) | |
| NP_001827.1 | |
| CMA1 | |
| A synthetic peptide corresponding to internal region of human CMA1. | |
| 100 μg | |
| Primary | |
| Human |
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