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CYP3A4, Goat, Polyclonal Antibody, Abnova™

Product Code. 16000128
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Quantity:
100 μg
Unit Size:
100µg
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16000128 100 μg 100µg
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Product Code. 16000128 Supplier Abnova Supplier No. PAB7000.100ug

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Description

Goat polyclonal antibody raised against synthetic peptide of CYP3A4.

This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. [provided by RefSeq

Sequence: C-KESRLEDTQKHR

Specifications

Antigen CYP3A4
Applications ELISA
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of CYP3A4.
Dilution ELISA (1:8000) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene CYP3A4
Gene Accession No. NP_059488.2
Gene Alias CP33/CP34/CYP3A/CYP3A3/HLP/MGC126680/NF-25/P450C3/P450PCN1
Gene Symbols CYP3A4
Host Species Goat
Immunogen A synthetic peptide corresponding to human CYP3A4.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1576
Test Specificity This antibody is not expected to cross-react with 3A5, 3A7 ot 3A43.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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