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KPNA2, Goat, Polyclonal Antibody, Abnova™

Product Code. 16059747
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Quantity:
100 μg
Unit Size:
100µg
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16059747 100 μg 100µg
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Product Code. 16059747 Supplier Abnova Supplier No. PAB6558.100ug

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Description

Goat polyclonal antibody raised against synthetic peptide of KPNA2.

The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq

Sequence: C-QVQDGAPGTFNF

Specifications

Antigen KPNA2
Applications ELISA, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of KPNA2.
Dilution ELISA (1:32000) Western Blot (0.1-0.5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene KPNA2
Gene Alias IPOA1/QIP2/RCH1/SRP1alpha
Gene Symbols KPNA2
Host Species Goat
Immunogen A synthetic peptide corresponding to human KPNA2.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3838
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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