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Invitrogen™ GP130 (soluble) Monoclonal Antibody (B-T2)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA125130
This item is not returnable.
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Description
MA1-25130 detects CD130 (gp130) from human samples.
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Specifications
| GP130 (soluble) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.09% sodium azide | |
| P40189 | |
| IL6ST | |
| Natural soluble CD130. | |
| 50 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Flow Cytometry | |
| B-T2 | |
| Unconjugated | |
| IL6ST | |
| 5133400A03Rik; AA389424; Ac1055; BB405851; CD130; CD130 antigen; CDW130; D13Ertd699e; EGK_16499; Gp130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6RB; IL-6R-beta; IL6R-beta; IL6ST; interleukin 6 signal transducer; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin 6 signal transducer receptor; interleukin receptor beta chain; interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; interleukin-6 signal transducer receptor; membrane glycoprotein; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha | |
| Mouse | |
| Ion-exchange chromatography | |
| RUO | |
| 3572 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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