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Invitrogen™ GPI Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA584103
This item is not returnable.
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Description
Immunogen sequence: VINIGIGGSD LGPLMVTEAL KPYSSGGPRV WYVSNIDGTH IAKTLAQLNP ESSLFIIASK TFTTQETITN AETAKEWFLQ AAKDPSAVAK HFVALST Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 93%.
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Specifications
| GPI | |
| Polyclonal | |
| Unconjugated | |
| GPI | |
| Amf; Autocrine motility factor; glucose phosphate isomerase; glucose phosphate isomerase 1; glucose phosphate isomerase 1 complex; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; glucose-6-phosphate isomerase; glucose-6-phosphate isomerase {ECO:0000250; GNPI; Gpi; GPI {ECO:0000250; gpi {ECO:0000312; GPI1; Gpi-1; Gpi-1r; Gpi1-r; Gpi1s; Gpi-1s; Gpi1-s; Gpi-1t; Gpi1-t; GPI-GlcNAc transferase complex subunit GPI1; hexose monophosphate isomerase; hexosephosphate isomerase; maturation factor; MF; Neuroleukin; neuroleukin {ECO:0000250; NK; NK/GPI; Nlk; NLK {ECO:0000250; Org; oxoisomerase; PGI; PGI {ECO:0000250; Phi; PHI {ECO:0000250; phosphatidylinositol N-acetylglucosaminyltransferase; Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1; Phosphoglucose isomerase; phosphoglucose isomerase {ECO:0000250; phosphohexomutase; phosphohexose isomerase; phosphohexose isomerase {ECO:0000250; phosphosaccharomutase; RGD:2727}; SA36; SA-36; sperm antigen; sperm antigen 36; sperm antigen-36; UniProtKB:P06745}; YGR216C | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 2821 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P06744 | |
| GPI | |
| Recombinant protein corresponding to Human GPI. Recombinant protein control fragment (Product #RP-104938). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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