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Invitrogen™ GPR17 Polyclonal Antibody
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Product Code. 11397183
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
11397183 100 μg 100µg
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Product Code. 11397183 Supplier Invitrogen™ Supplier No. PA519210

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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR17
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene GPR17
Gene Accession No. Q13304, Q6NS65
Gene Alias AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
Gene Symbols GPR17
Host Species Goat
Immunogen Synthetic peptide sequence (EGKTNESSLSAKSE) corresponding to the C-terminus amino acids of GPR17 (aa 353-366).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2840, 574402
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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