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GSK3179106, MedChemExpress

Product Code. 16463028
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Product Code. 16463028

Brand: Medchem Express HY100459

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Description

MedChemExpress GSK3179106 is an orally active and selective RET kinase inhibitor with IC50s of 0.4 nM, 0.2 nM for human RET and rat RET, respectively. GSK3179106 has the potential for irritable bowel syndrome (IBS) through the attenuation of post-inflammatory and stress-induced visceral hypersensitivity.

GSK3179106 is an orally active and selective RET kinase inhibitor with IC50s of 0.4 nM, 0.2 nM for human RET and rat RET, respectively. GSK3179106 has the potential for irritable bowel syndrome (IBS) through the attenuation of post-inflammatory and stress-induced visceral hypersensitivity.

Specifications

Chemical Name or Material GSK3179106
CAS 1627856-64-7
Color White
Purity Grade Notes Research
Molecular Formula C22H21F4N3O4
Quantity 10 mg
Solubility Information DMSO : ≥ 100 mg/mL (213.94 mM)
SMILES O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)CC2=CC=C(C(C(OCC)=C3)=CNC3=O)C=C2F
Molecular Weight (g/mol) 467.41
Formula Weight 467.41
Percent Purity 99.4%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-protein/nucleotide metabolism
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Research purposes only

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