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  6. GSTO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

GSTO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7206730 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16834164 20 μL 20µL
16824164 150 μL 150µL
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Product Code. 16834164 Supplier Proteintech Supplier No. 151241AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody detects both monomer (27-30 kDa) and dimer forms of GSTO1 (54-64 kDa).

GSTO1 (glutathione S-transferase omega 1), also known as p28 or GSTTLp28, is a 241 amino acid protein that localizes to the cytoplasm and contains both an N-terminal and a C-terminal GST domain. Expressed ubiquitously with highest expression in heart, liver and skeletal muscle, GSTO1 exists as a homodimer that functions as both a glutathione-dependent thiol transferase and a dehydroascorbate reductase. Specifically, GSTO1 catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. Human GSTO1 shares 70% sequence homology with its rodent counterpart, suggesting a conserved role between species. Polymorphisms in the gene encoding GSTO1 may be associated with the development of childhood acute lymphoblastic leukemia, Parkinson′s disease and Alzheimer disease.

Specifications

Antigen GSTO1
Applications Immunoprecipitation, Western Blot, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GSTO1
Gene Accession No. O09131, P78417, Q9Z339
Gene Alias GSTO 1, GSTO1, GSTTLp28, P28
Gene Symbols GSTO1
Host Species Rabbit
Immunogen GSTO1 Fusion Protein Ag7199
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114846, 14873, 9446
Target Species Mouse, Rat, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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