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Invitrogen™ HACE1 Monoclonal Antibody (8D3)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA517701

Product Code. 15373981

  • € 520.00 / 200µg

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Description

Description

MA5-17701 targets Hace 1 in ELISA, IF, IHC (P), and WB applications and shows reactivity with Human samples. The MA5-17701 immunogen is mouse monoclonal antibodies raised against His-tagged recombinant full length Human HACE1.

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HACE1
Monoclonal
1 mg/mL
PBS with 0.02% sodium azide
Q8IYU2
HACE1
Mouse monoclonal antibodies raised against His-tagged recombinant full length Human HACE1.
200 μg
Primary
Human
Antibody
IgG
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
8D3
Unconjugated
HACE1
1700042J16Rik; A730034A22Rik; BC025474; E3 ubiquitin-protein ligase HACE1; hace 1; Hace1; HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1; HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1; HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1; HECT-type E3 ubiquitin transferase HACE1; KIAA1320; SPPRS
Mouse
Protein G
RUO
57531
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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