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HACE1 Mouse anti-Human, Clone: OTI6H8, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies CF810071
This item is not returnable.
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Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.Specifications
| HACE1 | |
| Monoclonal | |
| Unconjugated | |
| HACE1 | |
| SPPRS | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 57531 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Western Blot | |
| OTI6H8 | |
| PBS with 8% trehalose and no preservative; pH 7.3 | |
| Q8IYU2 | |
| HACE1 | |
| Full length human recombit protein of human HACE1 produced in HEK293T cell. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
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