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  5. Thermo Scientific™ Harvest RC Centrate Chromatographic Clarifier

Thermo Scientific™ Harvest RC Centrate Chromatographic Clarifier

Product Code. 31931703 Shop All Thermo Scientific Products
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Flow Rate:
0.38 L/min.
3.07 L/min.
Closure Type:
1 1/2 in. Sanitary Connectors
Quantity:
1 Ea.
Unit Size:
Each
2 product options available for selection
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Product Code. Flow Rate Closure Type Quantity Unit Size
31931703 3.07 L/min. 1 1/2 in. Sanitary Connectors 1 Ea. Each
31931692 0.38 L/min. 1 1/2 in. Sanitary Connectors 1 Ea. Each
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Product Code. 31931703 Supplier Thermo Scientific™ Supplier No. 7100290390
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Description

Harvest RC Centrate Chromatographic Clarifier is designed to clarify CHO cell culture centrates from conventional or single‐use centrifuges. Available in a range of scaleable single use capsules enabling >95% product recovery and significantly reduced impurities.

Harvest RC Centrate Chromatographic Clarifier is a single-stage solution for clarifying CHO cell culture centrates from centrifugation systems. Using synthetic fibrous Q-functional AEX media, it clarifies by charge rather than size, reducing shear-related impurities. It delivers >95% product recovery while simplifying processes. Available in multiple sizes for seamless scale-up from bench to production.

  • Single-stage centrate clarification for process compression and streamlining of process development.
  • Enables de-risking of clarification process development, scale-up and tech transfer for faster speed to market.
  • Synthetic, functionalized fibrous media provides effective soluble impurity removal in centrate, including DNA and cell shear-related submicron particle reduction.
  • Predictable performance scalability for consistent centrate clarification at various process scales.
  • The single-mode electrostatic separation mechanism and high-throughput media enable product recoveries of >95%.
  • Provides comparable effluent quality to Harvest RC Chromatographic Clarifier for a modern clarification platform.
  • Lower consumption of buffer or water compared to depth filtration.
  • Alkaline-resistant capsules for pre-use sanitization.

Specifications

Autoclavable Not Autoclavable
Basis Weight 24.7 oz.
Bed Volume 547.78 oz.
Cap Material Glass Filled Polypropylene, Polyphenylene Oxide Polystyrene, Polypropylene, Silicone, Thermoplastic Elastomer TPE
Connectors Sanitary Connectors
Filter Type Single-use
Material Glass-filled Polypropylene, Polyphenylene Oxide, Polystyrene, Polypropylene, Silicone, TPE
Material (Membrane) Q-functional Polyamide
Pore Size 0.2 μm
Filtration Area 17.378 ft.²
Flow Rate 3.07 L/min.
For Use With (Application) Harvest and Clarification
Inlet Connection (English) Sanitary Connectors
Max. Pressure 49 lb./in.
Quantity 1 Ea.
Temperature (English) Max. 104°F
Temperature (Metric) Max 40°C
Volume (English) 547.78 oz.
Volume (Metric) 16.2 L
Height (English) 8.74 in.
Height (Metric) 22.2 cm
Diameter (English) 17.72 in.
Diameter (Metric) 45 cm
Weight (English) 24.7 oz.
Weight (Metric) 11.2 kg
Closure Type 1 1/2 in. Sanitary Connectors
Gasket Silicone
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