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Invitrogen™ HBG2 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5107140

Product Code. 17186943

  • € 550.00 / 100µL

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This item is not returnable. View return policy

Description

Description

Sequence homology: Cow: 100%; Dog: 77%; Goat: 100%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 93%; Rabbit: 75%; Rat: 83%; Sheep: 100%.

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HBG2
Polyclonal
Unconjugated
HBG2
abnormal hemoglobin; basic fibroblast growth factor; bFGF; Fgf2; Fgf-2; Fgfb; fibroblast growth factor 2; gamma-2-globin; G-gamma globin Paulinia; Hb F Ggamma; HBG2; HBGF-2; HBG-T1; hemoglobin gamma-2 chain; Hemoglobin gamma-G chain; hemoglobin subunit gamma 2; hemoglobin subunit gamma-2; hemoglobin, gamma G; heparin-binding growth factor 2; methemoglobin; TNCY
Rabbit
Affinity Chromatography
RUO
3048
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
P69892
HBG2
Synthetic peptide located within the following region: MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK.
100 μL
Primary
Human
Antibody
IgG
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