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Invitrogen™ HCN4 Monoclonal Antibody (N114/10), FITC

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA545432
Description
1 μg/mL of MA5-45432 was sufficient for detection of HCN4 in 10 μg of COS cell lysate transiently transfected with HCN4 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 130kDa. No cross-reactivity against other HCNs.
HCN4 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node.
Specifications
| HCN4 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS, 9.09mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4 | |
| O70507, Q9JKA7, Q9TV66, Q9Y3Q4 | |
| Hcn4 | |
| Fusion protein amino acids 1019-1198 (c-terminus) of rat HCN4. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat, Rabbit | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry, Microarray | |
| N114/10 | |
| FITC | |
| Hcn4 | |
| Bcng3; BCNG-3; brain cyclic nucleotide-gated channel 3; Hcn3; Hcn4; hyperpolarization activated cyclic nucleotide gated potassium channel 4; hyperpolarization activated cyclic nucleotide-gated cation channel 4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; hyperpolarization-activated, cyclic nucleotide-gated K+ 3; hyperpolarization-activated, cyclic nucleotide-gated K+ 4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; SSS2 | |
| Mouse | |
| Protein G | |
| RUO | |
| 100009452, 10021, 330953, 59266 | |
| 4°C, store in dark | |
| Liquid |
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