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Invitrogen™ HDAC3 Recombinant Rabbit Monoclonal Antibody (SC55-02)
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Description
HDAC3 Recombinant Monoclonal Antibody for Western Blot, IHC (P), ICC/IF
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Specifications
Specifications
| Antigen | HDAC3 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | SC55-02 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 |
| Gene | HDAC3 |
| Gene Accession No. | O15379, O88895, Q6P6W3 |
| Gene Alias | AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45 |
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