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HDAC4 Monoclonal Antibody (OTI4A4), TrueMAB™, OriGene

Product Code. 17524823
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100 μL
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30µL
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17524823 100 μL 100µL
17544823 30 μL 30µL
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Product Code. 17524823 Supplier Origene Technologies Supplier No. TA805010

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Description

Mouse Monoclonal Antibody

Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).

Specifications

Antigen HDAC4
Applications Western Blot
Classification Monoclonal
Clone OTI4A4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene HDAC4
Gene Accession No. P56524
Gene Alias AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
Gene Symbols HDAC4
Host Species Mouse
Immunogen Full length human recombit protein of human HDAC4 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9759
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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