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Invitrogen™ HDAC6 Polyclonal Antibody

Description
Suggested positive control: antigen standard for HDAC6 (transient overexpression lysate), NIH-3T3 whole cell lysate.
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Specifications
Specifications
| Antigen | HDAC6 |
| Applications | ChIP Assay, Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1.0 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | HDAC6 |
| Gene Accession No. | Q9UBN7, Q9Z2V5 |
| Gene Alias | CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6 |
| Gene Symbols | HDAC6 |
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