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Invitrogen™ HFE2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

€ 156.00 - € 453.00

Specifications

Antigen	HFE2
Concentration	0.5 mg/mL
Applications	Western Blot, Immunocytochemistry
Classification	Polyclonal
Conjugate	Unconjugated

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Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
17723314 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ PA5121914	20 μL	€ 156.00 20µL View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

17713314 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ PA5121913	100 μL	€ 453.00 100µL View alternative products Save Up to »		Please sign in to purchase this item. Need a web account? Register with us today!

Description

HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.

Specifications

Antigen	HFE2
Applications	Western Blot, Immunocytochemistry
Conjugate	Unconjugated
Host Species	Rabbit
Target Species	Human
Gene Accession No.	Q6ZVN8
Gene ID (Entrez)	148738
Immunogen	Lys234-Ser416 (Accession Q6ZVN8), with N-terminal His Tag.
Primary or Secondary	Primary
Content And Storage	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene	HFE2

Concentration	0.5 mg/mL
Classification	Polyclonal
Form	Liquid
Regulatory Status	RUO
Formulation	PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene Alias	2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; DL-M; Fidgetin; haemojuvelin; HEMOCHROMATOSIS; hemochromatosis type 2 (juvenile); hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; hemojuvelin; Hemojuvelin BMP coreceptor; HFE 2; HFE2; HFE2A; HJV; JH; MGC23953; OTTHUMP00000059680; repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC
Gene Symbols	HFE2
Isotype	IgG
Purification Method	Antigen affinity chromatography, Protein A
Product Type	Antibody

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Invitrogen™ HFE2 Polyclonal Antibody, Invitrogen™

Specifications

Description

Specifications

Documents