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Invitrogen™ HIP1R Monoclonal Antibody (1E1)

Product Code. 11554392
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Quantity:
100 μL
Unit Size:
100µL
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11554392 100 μL 100µL
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Product Code. 11554392 Supplier Invitrogen™ Supplier No. MA116750

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Mouse Monoclonal Antibody

Suggested positive control: HeLa whole cell lysate and rat brain homogenate, Hela whole cell lysate, antigen standard for IFT57 (transient overexpression lysate), rat brain protein.

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HIP1R
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1E1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.1% sodium azide
Gene HIP1R
Gene Accession No. O75146, Q9JKY5
Gene Alias AA410023; HIP12; HIP-12; Hip1r; HIP1-related protein; HIP3; huntingtin interacting protein 1 related; huntingtin interacting protein 12; Huntingtin-interacting protein 12; huntingtin-interacting protein 1-related protein; ILWEQ; KIAA0655; mKIAA0655
Gene Symbols HIP1R
Host Species Mouse
Immunogen Human HIP1 Related-TALIN Homology Region (57 kDa).
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29816, 81917, 9026
Target Species Human, Mouse, Rat, Bacteria
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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