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Invitrogen™ HIPPI Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529234

Product Code. 13423367

  • € 530.00 / 100µL

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This item is not returnable. View return policy

Description

Description

Recommended positive controls: 293T, A431, H1299, HeLa, Raji. Predicted reactivity: Mouse (92%), Rat (93%), Rhesus Monkey (98%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HIPPI
Polyclonal
Unconjugated
IFT57
4833420A15Rik; dermal papilla-derived protein 8; DERP8; Esrrbl1; estrogen-related receptor beta like 1; estrogen-related receptor beta-like protein 1; FLJ10147; HIP1 protein interactor; HIP1-interacting protein; Hippi; huntingtin interacting protein-1 interacting protein; huntingtin-interacting protein-1 protein interactor; IFT57; intraflagellar transport 57; intraflagellar transport 57 homolog; intraflagellar transport protein 57 homolog; MHS4R2; Vestrogen-related receptor beta like 1
Rabbit
Antigen affinity chromatography
RUO
55081
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.52 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q9NWB7
IFT57
Recombinant protein encompassing a sequence within the center region of human HIPPI. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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