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Invitrogen™ HIST1H2BD Polyclonal Antibody

Description
Recommended positive controls: 293T, A431, HeLa, HepG2, Neuro 2A , C8D30, NIH-3T3, Raw264.7, C2C12. Predicted reactivity: Human (99%), Rat (98%), Pig (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3.
Specifications
Specifications
| Antigen | HIST1H2BD |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | H2BC5 |
| Gene Accession No. | P58876 |
| Gene Alias | dJ221C16.6; H2B histone family, member B; H2B.1B; H2B/a; H2B/b; H2B/g; H2B/h; H2B/k; H2B/l; H2BC10; H2BC4; H2BC6; H2BC7; H2BC8; h2bd; H2BFA; H2BFB; H2BFG; H2BFH; H2BFK; H2BFL; HIRA-interacting protein 2; HIRIP2; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI; histone 1, H2bd; histone cluster 1, H2bd; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-D; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.a; Histone H2B.b; Histone H2B.g; Histone H2B.h; Histone H2B.k; Histone H2B.l |
| Gene Symbols | H2BC5 |
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