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HLA DR/DP Antibody (Bra-14), PE/Cy7, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-48006PECY7

Product Code. 18153038

  • € 569.00 / 0.10mL

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This item is not returnable. View return policy

Description

Description

HLA DR/DP Monoclonal specifically detects HLA DR/DP in Human samples. It is validated for Flow Cytometry.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HLA DR/DP
Monoclonal
PE-Cyanine7
PBS with 0.05% Sodium Azide
HLA-DRA
Human REH cells
0.1 mL
Primary
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Store at 4°C in the dark. Do not freeze.
Flow Cytometry
Bra-14
Flow Cytometry
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Mouse
Protein A or G purified
Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
3122.0
Human
IgG3 κ
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