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Invitrogen™ HM13 Polyclonal Antibody
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Product Code. 17121134 Shop All Thermo Scientific Products
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100 μg
Unit Size:
100µg
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17121134 100 μg 100µg
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Product Code. 17121134 Supplier Invitrogen™ Supplier No. PA5113271

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Description

Rabbit Polyclonal Antibody

HM13 Polyclonal Antibody for Western Blot, ICC/IF, ELISA

Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection. May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein. Involved in the intramembrane cleavage of the integral membrane protein PSEN1. Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139- dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HM13
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene HM13
Gene Accession No. Q8TCT9, Q9D8V0
Gene Alias 1200006O09Rik; 4930443L17Rik; 5031424B04Rik; AV020344; cb228; H13; H-13; hIMP1; histocompatibility (minor) 13; histocompatibility 13; histocompatibility minor 13; HM13; hm13 protein; IMP1; IMP-1; IMPAS; IMPAS-1; intramembrane aspartyl protease; intramembrane protease 1; minor histocompatibility antigen 13; minor histocompatibility antigen H13; MSTP086; presenilin-like aspartyl protease; presenilin-like protein 3; PSENL3; PSL3; Signal peptide peptidase; signal peptide peptidase beta; signal peptide peptidase like 1; SPP; SPPL1; Unknown (protein for MGC:134054); wu:fc11a06; zgc:56660; zgc:86862
Gene Symbols H13, HM13
Host Species Rabbit
Immunogen Recombinant Human Minor histocompatibility antigen H13 protein (336-377AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14950, 81502
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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