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Invitrogen™ HMGCR Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5106883
This item is not returnable.
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Description
Antibody detects endogenous levels of total HMGCR.
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) is a key enzyme in the mevalonate pathway, which is critical for the biosynthesis of cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in the production of cholesterol. Due to its central role in cholesterol synthesis, HMGCR is a primary target for statin drugs, which are used to lower cholesterol levels and reduce the risk of cardiovascular disease.
Specifications
| HMGCR | |
| Polyclonal | |
| Unconjugated | |
| HMGCR | |
| 3H3M; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); 3-hydroxy-3-methylglutaryl-CoA reductase; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; HMDH; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; HMG-CoAR; HMGCR; hydroxymethylglutaryl-CoA reductase; LDLCQ3; MGC103269; Red | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 15357, 25675, 3156 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P04035, P51639, Q01237 | |
| HMGCR | |
| A synthesized peptide derived from human HMGCR(Accession P04035), corresponding to amino acid residues E19-R69. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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