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Invitrogen™ HO-1 Monoclonal Antibody (6B8-2F2), PerCP
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA545348
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Description
1 μg/mL of MA5-45348 was sufficient for detection of HO-1 in 10 μg of rat kidney lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 32kDa. Does not cross-react with HO-2.
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
Specifications
| HO-1 | |
| Monoclonal | |
| 1 mg/mL | |
| 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative | |
| P06762, P09601, P14901 | |
| HMOX1 | |
| His-tagged Rat HO-1. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 κ |
| Western Blot, Immunocytochemistry | |
| 6B8-2F2 | |
| PerCP | |
| HMOX1 | |
| bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein | |
| Mouse | |
| Protein G | |
| RUO | |
| 15368, 24451, 3162 | |
| 4°C | |
| Liquid |
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