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Invitrogen™ HO-1 Polyclonal Antibody

Product Code. 16396544
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Quantity:
100 μg
Unit Size:
100µg
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16396544 100 μg 100µg
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Product Code. 16396544 Supplier Invitrogen™ Supplier No. PA577834

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Description

Rabbit Polyclonal Antibody

5 μg/mL of PA5-77834 was sufficient for detection of HO-1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 33kDa.

Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HO-1
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene HMOX1
Gene Accession No. P06762, P09601, P14901
Gene Alias bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein
Gene Symbols HMOX1
Host Species Rabbit
Immunogen Rat native full-length HO-1 purified from liver tissue.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15368, 24451, 3162
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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