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Invitrogen™ HOXA13 Polyclonal Antibody
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Product Code. 16547421
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Quantity:
100 μL
Unit Size:
100µL
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16547421 100 μL 100µL
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Product Code. 16547421 Supplier Invitrogen™ Supplier No. PA589567

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GPAGPAGAEA AKQCSPCSAA AQSSSGPAAL PYGYFGSGYY PCARMGPHPN AIKSCAQPAS AAAAAAFADK YMDTAGPAAE EFSSRAKEFA FYHQGYAAGP YHHHQPMPGY LDMPVVPGLG GPGESRHEPL GLPMESYQPW ALPNGWNGQM YCPKEQAQPP HLWKSTLPDV VSHPSDASSY R; Positive Samples: 22RV1, HT-29; Cellular Location: Nucleus.

HoxA13 and HoxD13 also bind to other BMP and TGF-beta/Activin-regulated Smad proteins including Smad1 and Smad2, but not Smad4. In humans and mice, loss of HOXA13 function causes defects in the growth and patterning of the digits and interdigital tissues. Analysis of HoxA13 expression reveals a pattern of localization overlapping with sites of reduced Bmp2 and Bmp7 expression in HoxA13 mutant limbs. HoxA13 regulates Bmp2 and Bmp7 expression, providing a link between HoxA13, its target genes and the specific developmental processes affected by loss of HoxA13 function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HOXA13
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Hoxa13
Gene Accession No. P31271
Gene Alias Hd; homeo box 1J; homeo box A13; homeobox A13; homeobox protein Hox-1.10; Homeobox protein Hox-1J; homeobox protein HOXA13; homeobox protein Hox-A13; HOX1; Hox-1.10; HOX1J; HOXA13; hypodactyly; RGD1562483; transcription factor HOXA13
Gene Symbols Hoxa13
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 140-320 of human HOXA13 (NP_0005132).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3209
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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