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Invitrogen™ HPD Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA527980

Product Code. 13432097

  • € 520.00 / 100µL

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Description

Description

Recommended positive controls: HepG2. Predicted reactivity: Mouse (90%), Rat (89%), Pig (88%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4). Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HPD
Polyclonal
Unconjugated
Hpd
4H GLOD3; 4-H HPPDASE; 4HPPD; 4-HPPD; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; f Alloantigen; F liver antigen; f protein; Fla; Flp; GLOD3; glyoxalase domain containing 3; HPD; Hppd; HPPDASE; Laf; PPD
Rabbit
Antigen affinity chromatography
RUO
3242
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P32754
Hpd
Recombinant protein encompassing a sequence within the center region of human HPD. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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