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Description
Positive Samples: Mouse testis, Mouse brain, Mouse spleen, Rat testis, Rat brain, Rat spleen, Raji, SH-SY5Y, U-251MG Immunogen sequence: MERAPPDGPL NASGALAGEA AAAGGARGFS AAWTAVLAAL MALLIVATVL GNALVMLAFV ADSSLRTQNN FFLLNLAISD FLVGAFCIPL YVPYVLTGRW.
H3 Histamine Receptor regulates the release of the neurotransmitters norepinephrine and somatostatin. In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons, in both the central and peripheral nervous systems, it acts as a presynaptic heteroreceptor. Multiple isoforms of H3 receptors are produced by alternative splicing. Histamine H3 receptor has been reported primarily in brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
Specifications
Specifications
| Antigen | HRH3 |
| Applications | ELISA, Immunoprecipitation, Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 7H8E6 |
| Concentration | 0.74 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | HRH3 |
| Gene Accession No. | P58406, Q9QYN8, Q9Y5N1 |
| Gene Alias | AW049250; G protein-coupled receptor; G protein-coupled receptor 97; GPCR97; G-protein coupled receptor 97; H3R; HH3R; histamine H3 receptor; histamine H3 receptor H3L isoform; histamine H3 receptor H3S isoform; histamine receptor; histamine receptor H 3; histamine receptor H3; Hrh3 |
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