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Invitrogen™ HSD3B7 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5101352
This item is not returnable.
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Description
Antibody detects endogenous levels of total HSD3B7.
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
Specifications
| HSD3B7 | |
| Polyclonal | |
| Unconjugated | |
| HSD3B7 | |
| 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; AI195443; BB098564; C(27) 3-beta-HSD; C(27)-3BETA-HSD; CBAS1; Cca2; cholest-5-ene-3-be; cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; Confluent 3Y1 cell-associated 2; HSD3B7; hsd3b7 {ECO:0000312; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; PFIC4; RGD:628727}; SDR11E3; short chain dehydrogenase/reductase family 11E, member 3 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 101502, 246211, 80270 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O35048, Q9EQC1, Q9H2F3 | |
| HSD3B7 | |
| A synthesized peptide derived from human HSD3B7(Accession Q9H2F3), corresponding to amino acid residues R122-E172. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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