missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 17817672

Invitrogen™ HSPB8 Monoclonal Antibody (3C12-H11), PE

Product Code. 17817672
Change view
Click to view available options
Quantity:
100 μg
Unit Size:
100µg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
17817672 100 μg 100µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 17817672 Supplier Invitrogen™ Supplier No. MA545256

Please to purchase this item. Need a web account? Register with us today!

This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
 View alternative products

This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45256 was sufficient for detection of HSP22 in 20 μg of whole rat tissue extract by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 22kDa. Detects endogenous and exogenous HSP22 in monomeric, dimeric and tetrameric forms in WB. Does not cross react with alpha crystallin.

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSPB8
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3C12-H11
Concentration 1 mg/mL
Conjugate PE
Formulation 2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene HSPB8
Gene Accession No. Q9EPX0, Q9JK92, Q9UJY1
Gene Alias Alpha-crystallin C chain; AU018630; AW413033; CMT2L; Cryac; crystallin, alpha C; D5Ucla4; DHMN 2; DHMN2; E2IG1; E2-induced gene 1 protein; H11; H11K; heat shock 22kDa protein 8; heat shock 27kDa protein 8; Heat shock protein; heat shock protein 8; heat shock protein B8; heat shock protein beta-8; heat shock protein family B (small) member 8; HMN 2; HMN2; HMN2A; HSB8; HSP; HSP20-like; Hsp22; HSPB 8; Hspb8; OTTHUMP00000239768; PP1629; Protein kinase H11; small stress protein-like protein HSP22
Gene Symbols HSPB8
Host Species Mouse
Immunogen His-tagged human recombinant HSP22.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113906, 26353, 80888
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.