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Invitrogen™ HSPB8 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110811

Product Code. 17158733

  • € 618.00 / 100µL

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Description

Description

Immunogen sequence: LLDDGFGMDP FPDDLTASWP DWALPRLSSA WPGTLRSGMV PRGPTATARF GVPAEGRTPP PFPGEPWKVC VNVHSFKPEE LMVKTKDGYV EVSGKHEEKQ QEGGIVSKNF TKKIQLP Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HSPB8
Polyclonal
Unconjugated
HSPB8
Alpha-crystallin C chain; AU018630; AW413033; CMT2L; Cryac; crystallin, alpha C; D5Ucla4; DHMN 2; DHMN2; E2IG1; E2-induced gene 1 protein; H11; H11K; heat shock 22kDa protein 8; heat shock 27kDa protein 8; Heat shock protein; heat shock protein 8; heat shock protein B8; heat shock protein beta-8; heat shock protein family B (small) member 8; HMN 2; HMN2; HMN2A; HSB8; HSP; HSP20-like; Hsp22; HSPB 8; Hspb8; OTTHUMP00000239768; PP1629; Protein kinase H11; small stress protein-like protein HSP22
Rabbit
Antigen affinity chromatography
RUO
26353
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9UJY1
HSPB8
Recombinant Protein corresonding to Human HSPB8. Recombinant protein control fragment (Product #RP-91460).
100 μL
Primary
Human
Antibody
IgG
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