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Invitrogen™ HTR1B Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA120650
This item is not returnable.
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Description
PA1-20650 detects 5-HT1B Receptor in human samples.
Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. In situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei.
Specifications
| HTR1B | |
| Polyclonal | |
| Unconjugated | |
| HTR1B | |
| 5-HT>1B> receptor; 5ht1b; 5-HT1B; 5-HT-1B; 5HT1B Receptor; 5-HT1B receptor; 5-HT1B serotonin receptor; 5-HT1DB; 5-HT-1D-beta; 5-hydroxytryptamine (serotonin ) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; 5-hydroxytryptamine receptor 1B; HTR1B; HTR1D2; HTR1DB; S12; serotonin (5-hydroxytryptamine (5HT)) receptor type 1B; serotonin 1D beta receptor; Serotonin receptor 1B | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 100009594, 100689321, 100717602, 15551, 25075, 317707, 3351, 397563, 403741 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| PBS with 0.1% sodium azide | |
| O08892, P28222, P28334, P28564, P46636, P49144, P79250, P79399 | |
| HTR1B | |
| Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human 5HT1B Receptor. | |
| 25 μg | |
| Primary | |
| Human, Mouse, Rat, Canine, Rabbit, Bovine, Hamster, Pig, Guinea Pig, Bat | |
| Antibody | |
| IgG |
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