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Invitrogen™ Human CTLA-4 His-tag, Recombinant Protein

Product Code. 17114263
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Quantity:
5 x 50 μg
Unit Size:
Pack of 5
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Product Code. 17114263

Brand: Invitrogen™ A42593

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Description

HEK293 cells Recombinant Protein

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P16410
For Use With (Application) Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
Formulation protein with 0.02% Tween 80, 140 mM NaCl, 2.7 mM KCl, 5% mannitol, 5% trehalose and no preservative; pH 7.4
Gene ID (Entrez) 1493
Name Human CTLA-4 His-tag
Quantity 5 x 50 μg
Source HEK293 cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form
Gene Symbol CTLA4
Specific Reactivity Human
Conjugate Unconjugated
Recombinant Recombinant
Form Lyophilized
Purity or Quality Grade ≥ 90%
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