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Invitrogen™ Human ALDH8A1 (aa 19-83) Control Fragment Recombinant Protein

Product Code. 30193921
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30193921

Brand: Invitrogen™ RP94718

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55298 (PA5-55298. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H2A2
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 64577
Name Human ALDH8A1 (aa 19-83) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; aldehyde dehydrogenase 8 family member A1; aldehyde dehydrogenase 8 family, member A1; aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase family protein; ALDH12; Aldh8a1; DJ352A20.2; Raldh4; Retinal dehydrogenase 4; retinal dehydrogenase type 4
Common Name ALDH8A1
Gene Symbol Aldh8a1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence LPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQS
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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