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Invitrogen™ Human Alivin 1 (aa 422-500) Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66268 (PA5-66268. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.
Specifications
Specifications
| Accession Number | Q86SJ2 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 347902 |
| Name | Human Alivin 1 (aa 422-500) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | adhesion molecule with Ig like domain 2; adhesion molecule with Ig-like domain 2; AI415330; Ali1; alivin 1; alivin-1; amigo2; AMIGO-2; amigo2 {ECO:0000312; amphoterin induced gene 2; amphoterin induced gene and ORF 2; amphoterin-induced protein 2; AW208913; DEGA; differentially expressed in gastric adenocarcinoma; differentially expressed in gastric adenocarcinomas; EMBL:AAO48951.1}; transmembrane protein AMIGO2 |
| Common Name | Alivin 1 |
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