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Gibco™ Human CCL22 (MDC) Recombinant Protein

Product Code. 10009032
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Quantity:
20 μg
Unit Size:
Each
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Recombinant Protein

Carrier-Free Reconstitution: The vial should be centrifuged prior to opening to bring contents to the bottom. The lyophilized powder should be reconstituted with sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C. Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles. Avoid repeated freeze/thaw cycles.

CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O00626
For Use With (Application) Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 6367
Molecular Weight (g/mol) 8 kDa
Name Human CCL22 (MDC)
Purification Method Sequential Chromatography
Quantity 20 μg
Endotoxin Concentration <0.1 ng/ μg
Gene Alias A-152E5.1; Abcd1; ABCD-1; Activated B and dendritic cell-derived; AW060611; CC chemokine ABCD-1; CC chemokine STCP-1; C-C motif chemokine 22; C-C motif chemokine ligand 22; Ccl22; chemokine (C-C motif) ligand 22; DC/B-CK; DCBCK; dendritic cell and B cell derived chemokine; macrophage-derived chemokine; MDC; MDC(1-69); MDC(3-69); MDC(5-69); MDC(7-69); MGC108943; MGC34554; RP24-69A20.1; Scya22; small inducible cytokine A22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); small inducible cytokine subfamily A (Cys-Cys) member 22; small inducible cytokine subfamily A (Cys-Cys), member 22; small inducible cytokine subfamily A, member 22; small inducible cytokine subfamily A22; small-inducible cytokine A22; STCP-1; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1
Common Name MDC
Biological Activity ED50 = 10-100 ng/mL; determined by the dose-dependent chemotaxis of human T-cells.
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Sequence Human CCL22 recombinant protein contains 67 amino acids
Content And Storage -20°C
Classification Carrier-Free
Endotoxin Level <0.1 ng/μg
Shipping Condition Approved for shipment on Wet or Dry Ice
Expression System E. coli
Protein Family Chemokines & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype Other Proteins
Research Category Inflammation
Product Line Gibco™
Purity or Quality Grade >98% by SDS-PAGE
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