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Invitrogen™ Human CKMT1A (aa 392-417) Control Fragment Recombinant Protein

Product Code. 30181734
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30181734

Brand: Invitrogen™ RP99584

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60387 (PA5-60387. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P12532
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 548596
Name Human CKMT1A (aa 392-417) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias Acidic-type mitochondrial creatine kinase; CKMT; Ckmt1; CKMT1A; Ckmt1b; Creatine kinase U-type, mitochondrial; creatine kinase, mitochondrial 1 (ubiquitous); creatine kinase, mitochondrial 1, ubiquitous; creatine kinase, mitochondrial 1 A; creatine kinase, mitochondrial 1 B; mia-CK; mi-CK; Mt-CK; ScCKmit; UbCKmit; Ubiquitous mitochondrial creatine kinase; U-MtCK
Common Name CKMT1A
Gene Symbol CKMT1A
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence YLIDCERRLERGQDIRIPTPVIHTKH
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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