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Invitrogen™ Human COX18 (aa 36-75) Control Fragment Recombinant Protein

Product Code. 30195007
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30195007

Brand: Invitrogen™ RP100829

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61317 (PA5-61317. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8N8Q8
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 285521
Name Human COX18 (aa 36-75) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias BC038311; COX18; COX18 cytochrome c oxidase assembly factor; COX18 cytochrome c oxidase assembly homolog; COX18, cytochrome c oxidase assembly factor; COX18Hs; cytochrome c oxidase assembly factor COX18; cytochrome c oxidase assembly homolog 18; cytochrome c oxidase assembly protein 18; Cytochrome c oxidase assembly protein COX18, mitochondrial; mitochondrial inner membrane protein COX18; Oxa1l2; RGD1559547
Common Name COX18
Gene Symbol Cox18
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence PTLPVWAVAPVSAVHANGWYEALAASSPVRVAEEVLLGVH
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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