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Invitrogen™ Human EXO5 Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110957 (PA5-110957. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'- directionality activity.
Specifications
Specifications
| Accession Number | Q9H790 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 64789 |
| Name | Human EXO5 Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | 3110037I16Rik; AV297100; C1orf176; defects in morphology 1 homolog; defects in morphology protein 1 homolog; Defects in morphology protein 1-like; Dem1; Exo V; EXO5; exonuclease 5; exonuclease V; hExo5; mExo5; probable exonuclease V |
| Common Name | EXO5 |
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