missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Gibco™ Human FGF-4, Animal-Free Recombinant Protein, PeproTech®
Recombinant Protein
€ 99.50 - € 1142.00
Specifications
| Accession Number | P08620 |
|---|---|
| For Use With (Application) | Functional Assay |
| Format | Lyophilized |
| Formulation | Protein with no preservative |
| Gene ID (Entrez) | 2249 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17896397
|
Gibco™
AF-100-31-50UG |
50 μg |
€ 409.00
50µg |
Estimated Shipment: 03-06-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
17876497
|
Gibco™
AF-100-31-250UG |
250 μg |
€ 1142.00
250µg |
Estimated Shipment: 03-06-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
17886517
|
Gibco™
AF-100-31-5UG |
5 μg |
€ 99.50
5µg |
Estimated Shipment: 03-06-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.Specifications
| P08620 | |
| Lyophilized | |
| 2249 | |
| Fgf4 | |
| -20°C | |
| <0.1 EU/μg | |
| Fgf4 | |
| Human | |
| Recombinant | |
| Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/mL, corresponding to a specific activity of ≥ 1 x 10^5 units/mg. | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| Protein with no preservative | |
| 19.7 kDa | |
| HPLC, SDS-PAGE | |
| RUO | |
| FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3 | |
| Protein | |
| Unconjugated | |
| GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL | |
| E. coli |