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Invitrogen™ Human GFER (aa 126-205) Control Fragment Recombinant Protein
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Quantity:
100 μL
Unit Size:
100µL
Description
Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59488 (PA5-59488. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen.
Specifications
Specifications
| Accession Number | P55789 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 2671 |
| Name | Human GFER (aa 126-205) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | ALR; Augmenter of liver regeneration; ERV1; ERV1 homolog; erv1-like growth factor; FAD-linked sulfhydryl oxidase ALR; Gfer; growth factor, augmenter of liver regeneration; growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration); growth factor, erv1 homolog; growth factor, erv1-like (augmenter of liver regeneration); hepatic regenerative stimulation substance; Hepatopoietin; hepatopoietin protein; HERV1; HPO; HPO1; HPO2; HSS; MNCb-0663 |
| Common Name | GFER |
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