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Gibco™ Human GM-CSF Recombinant Protein, PeproTech®
E. coli Recombinant Protein
€ 80.00 - € 3215.00
Specifications
Accession Number | P04141 |
---|---|
For Use With (Application) | ELISA, Functional Assay, Western Blot |
Formulation | protein with no preservative |
Gene ID (Entrez) | 1437 |
Molecular Weight (g/mol) | 14.6 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17850053
|
Gibco™
300-03-100UG |
100 μg |
€ 644.00
100µg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
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17851803
|
Gibco™
300-03-1MG |
1 mg |
€ 3215.00
1mg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
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17831823
|
Gibco™
300-03-20UG |
20 μg |
€ 194.00
20µg |
In Stock Log in to see stock. |
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17871803
|
Gibco™
300-03-250UG |
250 μg |
€ 1128.00
250µg |
In Stock Log in to see stock. |
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17830533
|
Gibco™
300-03-500UG |
500 μg |
€ 1924.00
500µg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
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17861303
|
Gibco™
300-03-50UG |
50 μg |
€ 385.00
50µg |
In Stock Log in to see stock. |
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17880033
|
Gibco™
300-03-5UG |
5 μg |
€ 80.00
5µg |
In Stock Log in to see stock. |
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Description
GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).Specifications
P04141 | |
protein with no preservative | |
14.6 | |
E. coli | |
RUO | |
colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim | |
Human | |
Recombinant | |
Lyophilized |
ELISA, Functional Assay, Western Blot | |
1437 | |
Human GM-CSF | |
-20°C | |
<1 EU/μg | |
CSF2 | |
Unconjugated | |
MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE | |
≥ 98% by SDS-PAGE gel and HPLC analyses. |