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Invitrogen™ Human GPM6A (aa 155-208) Control Fragment Recombinant Protein

Product Code. 30194680
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30194680

Brand: Invitrogen™ RP91159

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53588 (PA5-53588. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P51674
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 2823
Name Human GPM6A (aa 155-208) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias glycoprotein m6a; GPM6; Gpm6a; M6A; neuronal membrane glycoprotein M6-a; neuronal membrane glycoprotein M6-a-like
Common Name GPM6A
Gene Symbol GPM6A
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence YFNLWTICRNTTLVEGANLCLDLRQFGIVTIGEEKKICTVSENFLRMCESTELN
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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