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  5. Invitrogen™ Human HEXA ELISA Kit

Invitrogen™ Human HEXA ELISA Kit

Product Code. 17124533
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Quantity:
5 x 96 Tests
96 Tests
Unit Size:
Each
Pack of 96
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Product Code. 17124533

Brand: Invitrogen™ EH241RB

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Description

ELISA

Human HEXA quantitates human HEXA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human HEXA.

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Beta-hexosaminidase subunit alpha; beta-N-acetylhexosaminidase subunit alpha; EC 3.2.1; EC 3.2.1.52; Hex-1; HEXA; hexosaminidase A; hexosaminidase A (alpha polypeptide); hexosaminidase subunit A; hexosaminidase subunit alpha; Hexose aminidase A (alpha polypeptide); MGC99608; N-acetyl-beta-glucosaminidase subunit alpha; TSD
Assay Range 0.082 to 20 ng/mL
Assay Sensitivity 0.082 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 3073
Gene Symbol HEXA
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target HEXA
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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