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Invitrogen™ Human HTRA2 Synthetic Peptide

Product Code. 15206409
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. Quantity Unit Size
15206409 50 μg 50µg
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Product Code. 15206409 Supplier Invitrogen™ Supplier No. PEP0183
 Restricted Item
Estimated Shipment: 20-11-2026
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Description

Synthetic Peptide

This peptide corresponds to 15 amino acids near the carboxy terminus of human OMI. PEP-0183 can be used as a blocking peptide with polyclonal antibody PA5-20064.

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4). Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 27429
Species Human
Purification Method purified
Accession Number O43464
Common Name HTRA2
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Alias AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI
Gene Symbol HTRA2
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Storage Buffer PBS
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