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Gibco™ Human IFN-alpha 2 (alpha2a) Recombinant Protein, PeproTech®
Description
Recombinant Human IFN-alpha (2a) is a 19.3 kDa protein containing 166 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.
Specifications
Specifications
| Accession Number | P01563 |
| For Use With (Application) | Functional Assay |
| Format | Lyophilized |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 3440 |
| Molecular Weight (g/mol) | 19.3 kDa |
| Name | Human IFN-alpha 2 (alpha2a) |
| Purification Method | HPLC, SDS-PAGE |
| Quantity | 100 μg |
| Regulatory Status | RUO |
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Product Title
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