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Invitrogen™ eBioscience™ Human IL-12/IL-23 p40 Platinum ELISA Kit

For the quantitative detection of human IL-12/IL-23 p40.

Merk:  Invitrogen™ BMS2013TEN

Overige gegevens : Gewicht : 0.23750kg

 Bekijk meerdere types van dit product via de

Produktcode. 15541487

  • € 3055.00 / 10 stuks


Geschatte verzenddatum
bij leverancier 27-02-2019
Toevoegen aan winkelmandje

Inclusief: Aluminium pouch(es) with a Microwell Plate coated with polyclonal antibody to human IL-12/IL-23 p40
Biotin-Conjugate anti-human IL-12/IL-23 p40 monoclonal antibody
Streptavidin-HRP
Human IL-12/IL-23 p40 Standard lyophilized, 4ng/mL upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Beschrijving

Beschrijving

IL-12 is an interleukin produced by dendritic cells, neutrophils, macrophages and human lymphoblastoid cells as a result of antigenic stimulation. IL-12 is a heterodimeric cytokine encoded by IL-12A (p35) and IL-12B (p40). IL-23 is a heterodimeric cytokine that shares a subunit with IL-12 (IL-12B) along with an IL-23A (IL-23p19) subunit. Functionally, IL-12 increases the expression of vascular endothelial adhesion molecule-1 on the endothelium, directs leukocytes towards tumors and facilitates the ischemic-hemorrhagic necrosis of the tumor tissue. In comparison, IL-23 plays an important role in stimulating memory T-cells, and is required for the induction, expansion, maintenance and downstream effector functions of Th17 cells, which play a vital role in upregulating neutrophil chemokines and various pro-inflammatory cytokines.
Specificatie

Specificatie

P29460, Q9NPF7
Biotin
3593, 51561
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
10 x 96 tests
<10 pg/mL
50μL
Human
1 hr 20 min
Human
Interleukin-12 subunit beta precursor
4.7%
31.3-2,000 pg/mL
ELISA
Colorimetric Microplate Reader
ELISA
RUO
Plasma, Serum, Supernatants
Plasma (50μL), Serum (50μL), Supernatants (50μL)
2-8°C
4 hr 10 min
IL12B, IL23A
6.4%
HRP
Video's

For Research Use Only