Invitrogen™ eBioscience™ Human IL-12/IL-23 p40 Platinum ELISA Kit
For the quantitative detection of human IL-12/IL-23 p40.
Merk: Invitrogen™ BMS2013TEN
Overige gegevens : Gewicht : 0.23750kg
BeschrijvingIL-12 is an interleukin produced by dendritic cells, neutrophils, macrophages and human lymphoblastoid cells as a result of antigenic stimulation. IL-12 is a heterodimeric cytokine encoded by IL-12A (p35) and IL-12B (p40). IL-23 is a heterodimeric cytokine that shares a subunit with IL-12 (IL-12B) along with an IL-23A (IL-23p19) subunit. Functionally, IL-12 increases the expression of vascular endothelial adhesion molecule-1 on the endothelium, directs leukocytes towards tumors and facilitates the ischemic-hemorrhagic necrosis of the tumor tissue. In comparison, IL-23 plays an important role in stimulating memory T-cells, and is required for the induction, expansion, maintenance and downstream effector functions of Th17 cells, which play a vital role in upregulating neutrophil chemokines and various pro-inflammatory cytokines.
|Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers|
|10 x 96 tests|
|1 hr 20 min|
|Interleukin-12 subunit beta precursor|
|Colorimetric Microplate Reader|
|Plasma, Serum, Supernatants|
|Plasma (50μL), Serum (50μL), Supernatants (50μL)|
|4 hr 10 min|
For Research Use Only