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Invitrogen™ PD-L1 Human ELISA Kit

Sandwich ELISA Kit

Merk:  Invitrogen™ BMS221-2TWO

Overige gegevens : Gewicht : 0.23750kg

 Bekijk meerdere types van dit product via de

Produktcode. 15541727

  • € 674.00 / 2 stuks


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Beschrijving

Beschrijving

PD-L1 (Programmed death receptor ligand 1, B7-H1, CD274) is a a 40 kDa transmembrane protein and B7 family member. PD-L1 has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production, and PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion. Together with B7.1, PD-L1 can inactivate T cells and this relationship is a focal point of cancer therapeutic treatment. At least two isoforms of PDL-1 are known to exist.
Specificatie

Specificatie

Biotin
2 x 96 tests
Cell culture supernatant, serum, plasma (EDTA, citrate, heparin), amniotic fluid, urine, whole blood
Human
Aldesleukin, T cell growth factor, TCGF
ELISA
9.2pg/mL
50μL
IL-2
Video's

For Research Use Only