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Gibco™ Human IL-37 (IL-1F7), Animal-Free Recombinant Protein, PeproTech®

Product Code. 17886628
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Quantity:
250 μg
5 μg
Unit Size:
250µg
5µg
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Product Code. 17886628

Brand: Gibco™ AF200395UG

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This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human IL-37 is a 19.4 kDa protein consisting of 174 amino acids, corresponding to the mature activated form of IL-37. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NZH6
For Use With (Application) ELISA, Functional Assay
Format Lyophilized
Formulation protein with no preservative
Gene ID (Entrez) 27178
Molecular Weight (g/mol) 19.4 kDa
Name Human IL-37 (IL-1F7), Animal-Free
Purification Method HPLC, SDS-PAGE
Quantity 5 μg
Regulatory Status RUO
Endotoxin Concentration <0.1 EU/ μg
Gene Alias FIL1; FIL1 zeta; FIL1(ZETA); FIL1Z; IL-1 zeta; IL1F7; IL-1F7; IL1F7 (canonical product IL-1F7b); IL-1F7b (IL-1H4, IL-1 H, IL-1 RP1); IL-1 H; IL1H4; IL-1H4; IL1RP1; IL-1 RP1; IL-1 X; IL-1 x protein; IL37; IL-37; ILN; Interleukin; interleukin 1 family member 7; interleukin 1, zeta; interleukin 37; Interleukin-1 family member 7; Interleukin-1 homolog 4; interleukin-1 superfamily z; Interleukin-1 zeta; Interleukin-1-related protein; interleukin-23; Interleukin37; Interleukin-37
Common Name IL-37
Gene Symbol IL37
Biological Activity Measured by its ability to bind Interleukin-18 Binding Protein isoform a (IL-18 BPa) in functional ELISA.
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence MVHTSPKVKN LNPKKFSIHD QDHKVLVLDS GNLIAVPDKN YIRPEIFFAL ASSLSSASAE KGSPILLGVS KGEFCLYCDK DKGQSHPSLQ LKKEKLMKLA AQKESARRPF IFYRAQVGSW NMLESAAHPG WFICTSCNCN EPVGVTDKFE NRKHIEFSFQ PVCKAEMSPS EVSD
Content And Storage -20°C
Activity Measured by its ability to bind Interleukin-18 Binding Protein isoform a (IL-18 BPa) in functional ELISA.
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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